ISBN 9783843916097

978-3-8439-1609-7, Reihe Verfahrenstechnik

Juan Liang
Theoretical and experimental study of single and binary components adsorption of proteins onto ion-exchange chromatographic media

143 Seiten, Dissertation Technische Universität Hamburg-Harburg (2014), Softcover, A5

Zusammenfassung / Abstract

Serum albumin and hemoglobin were introduced to study the single and binary adsorption onto Q Sepharose FF. A comprehensive investigation combining experiments, mathematical models, and molecular dynamics simulations was performed. Through this research, a better understanding of the ion-exchange adsorption of proteins is obtained. These results are basis for the design, optimization and control of the ion-exchange chromatography of proteins.